TIBC (or transferrin) is typically used along with serum iron to evaluate persons suspected of having too much or too little iron. Usually, about one third of the transferrin measured is being used to transport iron. In iron deficiency, iron is low, but TIBC is increased. In iron overload, such as in hemochromatosis, iron will be high and TIBC will be low or normal.
Because transferrin is made in the liver, TIBC and transferrin will also be low with liver disease. Transferrin levels fall relatively rapidly when there is not enough protein in the diet, and so can also be used to monitor nutrition.

Not available.

Total Iron Binding Capacity (TIBC) and Transferrin Saturation.